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Sort of related to Jeff Tweedy and migraines: Miles Raymer has a column about special-needs kids and loud crazy indie rock, more specifically why it's a good idea to expose autistic kids to the Black Lips, and this jumped out at me:
Listening to a live band, Scholl says, is “a calming experience for some of them, especially the autistic kids. They really like the loud music.” Autistics can become overstimulated easily, in part because they have difficulty not perceiving all the tiny details that make up the big picture other people see. It’s possible that loud music works like a sonic version of the “squeeze machine” developed by autistic author Temple Grandin, creating a single profound sensation that damps down all that mental noise.