Osmosis Jones | Chicago Reader

Osmosis Jones

This cathartically disgusting adventure movie is set both inside the human body (the animated sequences were directed by Piet Kroon and Tom Sito) and out (the live-action sequences were directed by Peter and Bobby Farrelly). To Frank (Bill Murray), exercise means lifting food to his face, and food is broadly defined. After a spectacularly repugnant incident involving a hard-boiled egg, a deadly virus wages war with his immune system, and the personified combatants include a white blood cell and a cold pill with the voices of Chris Rock and David Hyde Pierce. The situations and dialogue are a dizzying concoction of puns and mixed metaphors that aren't just dubiously related to cell biology: it's at once a hygiene film (I couldn't stop washing my hands afterward) and a hygiene-film parody. It's also an action- and mucus-packed thriller and a tear- and vomit-jerking comedy-drama—the theme of the framing story is whether Frank's daughter can persuade him to adopt a healthier lifestyle before it's too late. Written by Marc Hyman; with Elena Franklin and the voice of Laurence Fishburne. 95 min.

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